Sildenafil/Vardenafil/Tadalafil

• It is used to treat erectile dysfunction (ED).
• It may be given to you for other reasons. Talk with your doctor.

• If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances.
• If you have kidney disease, liver disease, or hereditary eye problems like retinitis pigmentosa.
• If you have pulmonary veno-occlusive disease (PVOD).
•  If you have any of these health problems: unstable angina, heart attack within the last 90 days, chest pain during sex, heart failure, a heartbeat that is not normal, high or low blood pressure, or a stroke within the last 6 months.
• If you have ever had a long QT on ECG.
•  If you use drugs called “poppers” like amyl nitrite and butyl nitrite.
• If you are taking any of these drugs: Isosorbide Dinitrate, Isosorbide Mononitrate, or Nitroglycerin. Do not take these drugs with this drug. You may also need to avoid taking these drugs for some time after your last dose of this drug.
• If you take any drugs (prescriptions or OTC, natural products, vitamins) that must not be taken with this drug, like certain drugs that are used for high blood pressure, enlarged prostate, HIV, infections, and others. There are many drugs that must not be taken with this drug. Talk with your health care provider.
• If you are taking another drug that has the same drug in it.
• If you are taking another drug like this one that is used to treat erectile dysfunction or high pressure in the lungs.
• If you have sickle cell disease or bleeding problems, talk with your doctor.
• If you have been told that you are not healthy enough to have sex.

• Avoid driving and doing other tasks or actions that call for you to be alert until you see how this drug affects you.
• To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
• Avoid grapefruit and grapefruit juice.
• Talk with your doctor before you drink alcohol.

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call you doctor if any of these side effects or any other side effects bother you or do not go away.

• Flushing, headache, back pain, muscle pain.
• Upset stomach or heartburn.
• Signs of a common cold, stuffy nose, nose irritation, or throat irritation.

Warning/Caution: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

• Signs of an allergic reaction, like rash; hives; itching; tightness in the chest or throat, trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
• Signs of a severe skin reaction (Stevens-Johnson syndrome) like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in the mouth, throat, nose or eyes.
• Chest pain or pressure, a fast heartbeat, or an abnormal heartbeat.
• Dizziness or passing out.
• Severe headache.
• Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
• Change in eyesight or in the way you see color.
• Loss of eyesight.
• Ringing in the ears, hearing loss, or any other changes in hearing.

Call your doctor right away if you have a painful erection (hard penis) or an erection that lasts for longer than 4 hours. This may happen even when you are not having sex. If this is not treated right away, it may lead to lasting sex problems and you may not be able to have sex.

These are not all the side effects or interactions that may occur. If you have questions about side effects, call your doctor. You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at www.fda.gov/medwatch.

• Take with or without food.
• Do not take more often than told by the doctor.
• Do not take 2 doses at the same time or extra doses.

• Store at room temperature in a dry place. Do not store in a bathroom.
• Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
• Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

• If your symptoms or health problems do not get better or if they become worse, call your doctor.
• Do not share your drugs with others and do not take anyone else’s drugs.
• If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

This generalized information is a limited summary of diagnosis, treatment, and/or medication information. It is not meant to be comprehensive and should be used asa tool to help the user understand and/or assess potential diagnostic and treatment options. It does NOT include all information about conditions, treatments, medications, side effects, or risks that may apply to a specific patient. It is not intended to be medical advice or a substitute for the medical advice, diagnosis, or treatment of a health care provider based on the health care provider’s examination and assessment of a patient’s specific and unique circumstances.

Patients must speak with a health care provider for complete information about their health, medical questions, and treatment options, including any risks or benefits regarding use of medications. This information does not endorse any treatments or medications as safe, effective, or approved for treating a specific patient.